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Point mutation
A point mutation, or single base modification, is a type of mutation that causes a single ... A single point mutation can change the whole DNA sequence. ... . the amino acid glycine may be changed to... |
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DNA - mutations - Chemguide
Copying errors when DNA replicates or is transcribed into RNA can cause changes in the sequence ... If a stop codon was produced in the middle of the gene, then the protein formed would be too short, ... What if you do it for more than one? |
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A case study of the effects of mutation: Sickle cell anemia
The disease is caused by a mutated version of the gene that helps make ... People who carry only one copy of the sickle cell gene do not have the disease, but may ... but the gene that she carries still affects her, her cells, and her proteins : ... the mutation in the DNA slightly changes the shape of the hemoglobin molecule, ... |
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Mutation
Changes in these portions of the DNA do not alter any gene and are thus silent. ... Not all portions of a protein are equally important for the function of that protein ... This kind of mutation often leads to a classic recessive allele--an allele which does not produce a ... . For instance, ultraviolet (UV) radiation can causemutation... |
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Protein Function and Malfunction in Cells - Modern Genetic Analysis ...
Thus protein function depends absolutely on the DNA sequence of its coding gene. ... produce movement in the cell and membrane-bound proteins that regulate ... . Changes that do not affect the function of a protein are called silent mutations. ... A common cause of genetic disease in humans is enzyme deficiency caused ... |
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SparkNotes: Genetic Code: Mutations
Mutations are errors in codons caused by changes in nucleotide bases. ... on coding for amino acids, which can in turn affect what proteins are produced, ... insertion or deletion, in which a base is either incorrectly inserted or deleted ... is called extragenic supression because the second mutation does not occur in the gene. |
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Effects of Mutations on Protein Function: Missense, Nonsense, and ...
How does a tiny point mutation change the way a protein works? ... In biology, a mutation is any change in the nucleotide sequence of DNA. ... We call it a missense mutation because it causes the protein to be incorrectly translated from the original ... We have to stop short, and now the magikeratin won't be produced at all. |
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Mutation by Base Substitution - McGraw Hill Higher Education
Addition and deletion mutations generally produce nonfunctional proteins or no protein product ... A mutation occurs by base substitution when an incorrect base is incorporated ... A mutation that causes a change in a single nucleotide in DNA. |
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BBC - Higher Bitesize Biology - Mutations : Revision
A gene mutation is a change in the order of bases on a strand of DNA. ... Only one of the strands of DNA is involved in protein synthesis. ... The base sequence on the mRNA produced by the DNA is altered. ... is converted into toxic substances; the toxic substances cause irreversible damage to the developing brain. Page; 1 ... |