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Polycomb Group Response Elements in Drosophila and Vertebrates
Polycomb Group Response Elements in Drosophila and Vertebrates ... . They studied targets that bind the PcG proteins Pho, Sce, Pc, Ph, and Psc, and ... . Only a few of the hundreds of PREs identified in genome-wide studies ... ... A potential human PRE was identified in resting T cells downstream of the ... |
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Cavalli Lab - The Polycomb and Trithorax Group proteins page
Polycomb group (PcG) and trithorax group (trxG) proteins regulate expression patterns ... binding to specific DNA elements called Polycomb ResponseElements (PREs). ... PREs have only been characterized in Drosophila so far. ... .. Homologs exist in human, but it is unknown whether they form a complex |
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Genome Regulation by Polycomb and Trithorax Proteins
These elements, called PcG and trxG response elements (PREs and TREs), ... and trxG proteins are recruited to chromatin and how they regulate their target genes. ... . Although the recruitment of PcG proteins was only slightly affected ... . The components of the PRC2 complex in flies, mouse and human are ... |
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according to this theory, sleep is a product of evolution.? |
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what is a sharks body covering? |
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The Role of Polycomb Group Proteins in Cell Cycle Regulation ...
Martinez@igh.cnrs.fr/ Giacomo Cavalli; Institute of Human ... with specific DNA regions termed PcG response elements (PREs), ... .. In addition, Drosophila is the only organism in ... . may be regulated by PcG complexes in vivo is too large to give a ... Ring1B, they show distinct patterns of expression during ... |
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Regulation - Interactive Fly, Drosophila
They share stretches of homology across their entire lengths and are very ... In particular, the human and mouse proteins appear strikingly identical, with few ... . early in S phase while the arrest of H1 transcription only occurs at the end of S phase. ... .. and Polycomb continuously associate with their response elements on the ... |
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Polycomb complexes act redundantly to repress genomic repeats ...
In the fly, Polycomb response elements that act as memory modules for ... This view might be too simplistic, as considerable biochemical heterogeneity has been ... of target loci or whether they have a modulatory role for gene expression. ... . A set of 329 genes was derepressed only after the combined loss of PRC1 and ... |
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Intergenic transcription through a Polycomb group response...
Polycomb group response elements (PREs) mediate the mitotic inheritance ... of Drosophila, intergenic PRE transcripts can be detected not only ... In the developmental regulation of globin gene expression at the human β-globin locus, ... .. We reasoned that this time frame of transcription may be too short to ... |
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A dimeric state for PRC2 - Nucleic Acids Research - Oxford Journals
Here we show that reconstituted human PRC2 is in fact a dimer, using multiple ... Even though it contains at least two RNA-binding subunits, each PRC2 dimer binds only one RNA molecule. ... In Drosophila PRC2 is recruited to chromatin through polycomb response elements (reviewed in (11)). Despite ... |
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RET Finger Protein Is a Transcriptional Repressor and Interacts with ...
Among Polycomb group genes, only E(Pc)and Enhancer of zeste (E(z)) were shown ... Here we report that RFP interacts with human EPC and that RFP itself ... . Serum response element (SRE), cAMP response element (CRE), and ... to the EPcA domain of Drosophila Enhancer of Polycomb (E(Pc)) gene by ... |